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KMID : 0882420090770020236
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Korean Journal of Medicine
2009 Volume.77 No. 2 p.236 ~ p.240
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Granulocytic sarcoma presenting in two patients without leukemia
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Lee Kyu-Ho
Kim Hyun
Choi Khan-Young
Lee Ju-Hee
Han Hye-Sook
Lee Ki-Hyeong
Kim Seung-Taik
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Abstract
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Granulocytic sarcoma (GS) is a rare extramedullary tumor composed of immature myeloid precursor cells. GS is associated with acute or chronic myeloid leukemia; it has rarely been reported in non-leukemic patients. We report two cases of GS with unusual presentations; neither had bone marrow involvement. The first case was a GS presenting with multiple intra-abdominal masses in a 43-year-old man. Computed tomography (CT) of the abdomen showed masses in the small bowel and right adrenal gland. The second case was a patient with a GS presenting with symptoms of spinal cord compression in a 32-year-old man. Magnetic resonance imaging (MRI) showed an extradural mass in the spinal canal at the T3-T5 levels. Blood smear and bone marrow studies were normal. These cases show that GS should be included in the differential diagnosis of intra-abdominal masses and extradural spinal cord tumors, even in the absence of leukemia.
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KEYWORD
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Granulocytic sarcoma, Abdominal mass, Spinal cord compression
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